The ECOTOX Plastox DB provides consolidated human and environmental toxicity data, covering aquatic acute and chronic toxicity, reproductive toxicity, and endocrine disruption potential, for over 12K chemicals used in the plastics industry. Data are sourced from ECHA and PubChem and can be queried by CAS number.
For example, a search for Butylhydroxytoluene (CAS 128‑37‑0) returns:
Aquatic toxicity classification
Aquatic Chronic 1 – Very toxic to aquatic life with long‑lasting effects (H410).
Reproductive toxicity
Suspected of damaging fertility or the unborn child (H361).
Endocrine disruption status
Under assessment as an endocrine disruptor (EUH381/EUH431).
PBT classification
Not classified as Persistent, Bioaccumulative, and Toxic (PBT).
Listed in international regulations
Not listed under Stockholm Convention, Basel Convention, or REACH restricted substances.
Reported uses in plastics
Antioxidant; Biocide; Catalyst; Colorant; Crosslinking agent; Filler; Heat stabilizer; Initiator; Intermediate; Light stabilizer; Lubricant; Odor agent; Other processing aids; Plasticizer.